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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '49ba824be03f8dacdb76b024c8b68f32105fc5bf247c90f26046f49295b37ca5' 
  AND token = 'DiFem6MrSEelq56tI+4WxKP4J5gSKaocM7ANItcoOis=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}