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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4097eadb0300a6fe31d82a9da130abd9b6d9d9db6fd9cb7e7d196cbaf80b4035' 
  AND token = 'nmwzHLVhx3J3LfAB7KKOH6VRWv4dM1VNRvLKI+TRNbA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}