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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '353a9b5590629c07c6fb3eef94e283b278ad2e7ac7362b5ed88a813dbc0d9464' 
  AND token = '6mLk0ex6V3b7TqQjrOZsde06vJ28qV952rse0xNl/Bg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}