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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'acb9e017c03002f555ca790330edebb3acc8f0724593228c9cb0630eeef50604' 
  AND token = 'K22PKgXkGnvOUgZH9s3kGVqc327KT4NT3kqYfaiA/EY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}