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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8e313aa0576f61b0c1351dfca1805ccfed5f749d7aa42ee7d623712adb68df99' 
  AND token = 'o50n7wRXLhIb2OeChi0sMnPb5mpzFi1kdYlaZ147fzw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}