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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '345174cbddd6869c28cc5b8c1411cc7bd282058ade2d3d40f163a7adf153f96c' 
  AND token = 't4bjmnEWLQ42Xpu3gE8kebqaafL3tKYGelGGQoa44Eo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00047

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}