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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1852bc47d718174a3d0094ea10eec26b9c07599709007ce0b1ef1de7c1802bb5' 
  AND token = 'EstI4hsdmw5VtsxQNvGw+lIPn0/461MICIvE8Ojt7EE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}