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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2124965ff9a908d26078ee389a82a67f626da8e9bfac3b350171d16f2c8a638b' 
  AND token = 'wE4uPQ2MNh2AbgBSaEH8xP7cTUosgMMNMkzpw0LnAPM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00051

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}