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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '43fc85a68f110f2ef1c965a3efb2b1c69f2c25873ca8b1e1409c3596a3ebcf60' 
  AND token = 'yfNuD0zdvC7uAcm++vyjhszExHj0Y0LwFNbWay9MRRA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}