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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f66c51ba4e50abb201a7d0b8c0e625029e46d4ece427066903d8d8522b9c03b8' 
  AND token = 'lHTFurmoJWTSb+jvcWu69DDEr9xR3o/AZ/AK4SaYvj0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}