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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '44a7bcade3cc2eea4e1e970c6fe9d81ca8ac6ad5a333bff0540dd848811db75c' 
  AND token = '10ABNh0wNeRk8OSvO0cpoqShG11MUrAwTXKdNQOOVb8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}