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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1bc81fe9dd329d3973daf033e8ebdeb94385ef146ee6192867ed6d2a800061fa' 
  AND token = 'XU8+iL1A8tpSXUtMtpSRh0+0wQ54Tzw7Cfuhqd9JoSw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}