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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c2e30a77b2fe3755fe278331669b6924eb28ac7df81d326e382231883c254c10' 
  AND token = '6C/m5BDeP3cuGl+4cfYAg+GT2Oor3ZNNyqhBfPywm1Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}