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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9d0a5719de28c2649ec79737c2b22b64106d1fec4d50ec7834c57c41d12c0d32' 
  AND token = 'XgA2Tl/h6ZUAlyvcz53uU/T+xNLWIWdKOgqqHE3m92c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}