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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'adbea7b3025d54a2631d811c60ba1d79f4da1b2029fa0981f72e6f79f1485419' 
  AND token = 'Ik3LhU4BfsO0SSVQJEegObqbY0UGri5zrdGN6Gir5Bo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}