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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a75e865215763df992459f2b01fa41868df06029023877268a6d3bf95944964d' 
  AND token = 'twd8ZdSNMUGmQhiIGbWEPVu3e4Y0jVc26MsvB9BoyLQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}