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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1a9dcd9b26e0cf952be8b52d7df43d33574f4087bd7d2c90f4f3021d7a1bd265' 
  AND token = 'DnoKII8bHWiJVPoKswJU0vsSKurCLQpWlfbEwuQYM4g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}