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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b8d351cba72f78d9af1d8f07b7b3e0a3fa872f2237ac7ea56f39bcd064083fd5' 
  AND token = 'Th6jmmTQl/8h8KXQ8DwUJiZ2vkoacelWDa2V7SNZTlc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}