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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2a4b823defc32187dc773a1ff24ad012004eee8b2b6f5a7fe082acfe72ff890a' 
  AND token = 'PpgKQWVuHkLQV2XDZLqL+/19jcIw4Z7ifRltWVpX1GA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00052

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}