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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7c0d4380f34c2ed5726d8004c15863cc8068276ad1d3ce33efd664ee7a5bd8c6' 
  AND token = '61VtGBRKp8+gQ9JB7/k0vEU/43rBPaiGFHwFBGeKSlw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}