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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fc6ef4d45e4cbc39efe4aefa728bde010ff483e452d87502ddcfe8d219e4e892' 
  AND token = 'DTG1oV6/1zLBs6Iz5CFRtp9m8rBObpfDvKY3Eb2YgnQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}