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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd375e74ac29d9e1d557818ae7cf9d7b6bc86b1b3dc5e0d60fa161d8c4669f552' 
  AND token = 'FObxrjlhhx5vleqU/GjAbEcg9ywv26CSULIP5DmFGkg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}