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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c10fa7fafc82b67e13e218843dc85fd92e18ae90f7c410243644c4825c45b6c2' 
  AND token = 'F+z7TLwLOXoIPCmyzGETW/0/u+kT2FPGh2uYAH+5qAM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}