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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a28b6c3482197e07a5bf66810623e3eb992a3db5cf9f5f76e8e9c40acdf044f5' 
  AND token = 'm1jmpQM4IE47nMxZnhK7XIiqb0vUy+iX8UO6MxnQWc0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}