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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1afbfb37f354712cb168fb2475947eebdc1e2fdd67416b146a2335c20cbfa607' 
  AND token = '+CPmQIEgU8u2qE2Uw/yxIW/t0HV6QdouOtXHMeghMsI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}