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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e648e74315c4c7e0e561dabdeae8aea017ee31430e0da3aa2d5a56a64eff2deb' 
  AND token = 'UswtLnILoMTqmWCXupovuVaq6sqre18rvdA8inQ2Gds=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}