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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2b85956a8ccf6a4453ac242e0f5d49d90bc862b8c11eeb45579d72d5c037e5c8' 
  AND token = 'VNpeX9DldcNMiGJ/7YYmxnB9Qkgr6KtmGrQi3Yi7jk0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}