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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'bd649e940cb4ac3be7a9df5827b803b1eff26275544550622f7e2d24ab7d172e' 
  AND token = 'QC01rj0c2A35hCURXp7Dv4Z6aRgr+kiXRcZk8xIS3fk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}