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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f5daab31ba5c540b9aa49e93cfa009724e61cba911396310bd8e1f8da6ae40fe' 
  AND token = 'PQ+uHM/tECgZfcpk9lqdPa3VCQUqTELsaVGW2dqBys4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}