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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2c2a104283d305a6a8bfbf45789153a03e2bb8c3776b743ce37ac61da08a4f79' 
  AND token = '4QVVVZVcRONBYbU2vtvcbGFGcpOoq+tleq4bHTMDGdk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}