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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '16d064a794dec81dea969056b2bdaa647b792169d871a56b06b34d321c6768e1' 
  AND token = 'M21/7StLd9k51T9pO7JeAKsVzzO+8hE44u0itWttRUg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}