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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1e3c661a1d2cd5fafacd427b30f6bbbe05dfd9829b8a5e4dae284af00c8cadce' 
  AND token = 'oLA66WC1pA82M0/XtVq+5zadzdMB+fIhwY3Is/kGGoE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}