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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8c467bb93481d02d18017784283d3cbb8f4e4c69005b7c9037f2b6b547b8eb29' 
  AND token = 'xo3Ix6QLDc8HZ0NHCMCPcwsVFJ4Seu7o1oIhVwFZ/OY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}