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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a174f1754eb791e4581e2ed70afcf33bd89a6f27162b884e660d7692b7839676' 
  AND token = 'k9KzWE0Tg7txhB4TCAaw188ztRwdfWdgxBctvCraQSU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}