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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '66fa7adb7c94f202e6c922970808455d3da4b7c7366c85c0494bb551b7775dcb' 
  AND token = 'EOP84jMs54E4Ecl4u1dIQH7hF1OsCgi9gSwO6N8EItc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}