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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2b698c60daf30329335f8521b8028a309b076b2b5feb913bcefd18fa230c3256' 
  AND token = 'QDWNbSkouqRTWBQa8aGYWEF3cQEMjTBWb6yKfP/1mCc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}