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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c189f74358876c86d07ab063aea1c2a627cbb3c2cc93994bf7bc7c1a031d71f7' 
  AND token = 'T3QmGUnxWsdL/W3B/zw2RQL3Xet4Ef4vcn6g51VqfQ8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}