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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8f7b328f245b15c3f65f8edc127e159abd54328d3eba1bebfb4036f7190265de' 
  AND token = 'dfDkY129waSmZFrbswqdDFGXn/8XZn/tgFGkh1Pkv+I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}