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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9b869a7b5d4bb12a293548fdfa24c87b9f74c5b242af5b215710f233cd77203c' 
  AND token = 'VwNxYAkzou0yJ+5DsLYIrFtXLxDI8l469xzkszJ5mww=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}