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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5b636925700d029d469f5e2935f0314d46440c75d6725050cf11115b281a5c7c' 
  AND token = 'supJ3oHxxrXd9g4/ePKBEW9xBPDtJrfibuvBwHkEhzc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}