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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e0ed40068b5df48fa77cf7c928de52e3b04e3dfaa5c32e7bd069d7d6ebed3355' 
  AND token = '6NTK0PPexY4DvV+MFctB9w0wFAqk3EvIsYnJQI4Nnfw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}