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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '949972aaedd1819dbb3e25ed4fe4e663f699921664c7de99b9d0ee9bda02cc0a' 
  AND token = 'M+lfdjqPTpROIqfLMscd+VRVZV0CWea7FeoOrd4CqhU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}