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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd5f3a6826bc826a27eec8bfdb3aaf4cc7908c00a721bb7901a93a7e818b1f387' 
  AND token = 'hIDiZP+oy1O0soxSKIF+u/75I7Gz3f1KSOF9Sw/x1/o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}