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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '556e45ffb029a45db0ab0500fc6d9fd0a19a86a88171c85a2fd079623a14fb65' 
  AND token = 'p5KbWtBPhFiAVfKAUJwfw/oqQKWlyoKyfiqS0KR9Fdw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}