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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a46b10817423638429481c5d853456f46a499ee297740345547b6c7fce5d04dd' 
  AND token = 'uaxIKbKj5dWu+7Uo4JubU5c4oaNs4MGug1yW7hF4x1E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}