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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3486c752388ab5aa4811619c2717cc5f6db6d4ec6036e3ff92bec2a41df353c2' 
  AND token = 'qDunhQ6wlUTfH9r34JVIhhltvYrygyVoOw5Y3o23xv0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}