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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '575477a827d79a2209cdc6a6bb3178c3134c6566b50518bc73290ac04198bb6b' 
  AND token = 'Ca8kHwSjFbMA+zhc8oU2DmN8nEKizWOBWB/w2W8yhz8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}