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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e403acef295a608919cbd8f95eb6ef22873cf91b836f0e42c16fc14ac5d4c4a5' 
  AND token = 'TGB6c5/TM8Nf/ffLDJyrk1x3kC1HmkZnMNsBIm4+Z8w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}