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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '486e5430df610df852ba4fb7fe19c4334a28c143c8a7011e2ea3d53c6e237bb2' 
  AND token = 'qv8NRp5kf+ghJHw7qHCCuFvTIg4mgGgMof69WHbpykk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}