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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '500e62005efc313a31d2a4dfee8ed12868b27500d019777dd78e97f7d56c2e0e' 
  AND token = 'w7WmdbrijX6bJh75jmpSrbnb1ZfR0BrdLtb1ZV1Rp58=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}